



Detoxification on a Cellular Level
The Science of Advanced TRS
On its own, your body has to go to a lot of work to neutralize and remove toxins, if it is able to remove them at all. For example, lead and mercury are notoriously difficult to remove. As a person’s body becomes more toxic with heavy metals, it becomes less able to remove them.
Zeolites are Nature’s own toxin removal system. In Nature, zeolites are an important part of the water cycle, helping to ensure plentiful, fresh, pure groundwater for your health. In the body, zeolites also act as a clean-up system, removing toxic substances that have accumulated in the body from the foods we eat, and from the environment in which we live. These accumulated substances cause our body to work overtime, diverting energy needed by cells and tissues, and weakening the body’s natural ability to heal itself. As these substances are removed, our body becomes healthier. The zeolite in Advanced TRS is nanosized (1/3,000,000th of an inch) to maximize access to the toxin-absorbing centers in the material. The individual particles are enveloped by layers of water which allows them to travel efficiently in the body to do their job.

Independent 3rd Party Testing & Resource Materials
Advanced TRS promotes detoxification by attracting, trapping, and removing heavy metals, toxins, and other contaminants from the body. At the cellular level, removing such toxins allows cells to return to their healthy equilibrium and function.
Advanced Laboratories


Ideal Particle Size = Effectiveness
Being nano-sized, the individual particles in Advanced TRS are maximally efficient at absorbing toxins. Think of a bath sponge. When you put it in water, the water flows into to sponge from the outside in. Now imagine your bath being filled with millions of floating foosballs the size of the holes in your sponge.
The water will carry them in at the beginning, but pretty quickly, the holes in the sponge will be clogged up, leaving a large part of the center of the sponge, dry, and unused. That is what happens when large zeolite particles are used in detox products. This means more than half of the material cannot be used. While zeolite itself is non-toxic, common sense tells us we should take only what we can optimally use, and what is effective, to reach better health.
That is what happens with Advanced TRS, virtually no excess, with extraordinarily effective results. One serving will not do a complete detox. Over time, consistently taking this product will remove toxins safely, gently and without the typical effects of harsh medical chelation agents.

learn the science.
What is the difference between lab-made zeolite and mined zeolite?
Lab Grown zeolite is made in the laboratory under controlled conditions and with controlled composition. Mined zeolite is extracted from the earth in its natural form and is usually processed to remove attached impurities. Lab Grown zeolite can only contain the elements that are put in as part of the controlled process. Mined zeolite may contain trace amounts of many different kinds of elements. Of the 245 unique zeolite frameworks that have been identified by the International Zeolite Association Structure Commission, over 40 are naturally occurring.
Naturally occurring zeolites are rarely pure and are contaminated to varying degrees by other minerals, metals, quartz, or other zeolites. Some of these impurities are simply adsorbed inside the zeolite’s pores, while others are an integral part of the structure. Acid treatments at high temperatures can remove many of these impurities, but as more structural atoms are extracted, the integrity of the zeolite framework becomes compromised, and the important toxin-binding cages begin to collapse. At this point, the zeolite becomes increasingly less effective as regions inside the structure become blocked. In other words, increasing purity is balanced by decreasing function, and it is difficult to completely purify a naturally occurring zeolite from all its impurities and still retain full potency.
There are no such things as “different-sized zeolite molecules”. The zeolite in Advanced TRS is not a molecule of zeolite, it is a cluster of multiple zeolite cages that together forms an object that is only nanometers large. It is not possible to create a structural formula for a specific particle size, instead structural formulas are created on the basis of the zeolite’s unit cell, the minimum size repeating unit. This formula is the same regardless of particle size.
A representation is given by (Na2, K2, Ca)3Al6Si30O72·24H2O. The crystal structure of clinoptilolite has large 12-ring pores, the effective pore size of the zeolite excludes molecules larger than ~0.9 nm. Because of its wide use in agriculture and industry Clinoptilolite has been named the mineral of the 21st century by The International Mineralogical Association. Clinoptilolite has been used with success in animal feed at less than 2% by weight and for the purpose of an anti-caking flow agent.
To produce pure, synthetic clinoptilolite, silica, alumina, and alkali sources with initial Si/Al ratio from 3.0 to 5.0 are heated in an autoclave for 1–10 days at a temperature range from 120 to 195 °C. The Clinoptilolite begins to assemble in tiny crystals, whose crystallization rate and crystallinity is controlled by seeding and manipulation of the reaction conditions. Instead of direct heat, microwave, ultrasound and high pressure may be used.
Farjoo A, Sawada JA, Kuznicki SM. Manipulation of the pore size of clinoptilolite for separation of ethane from ethylene. Chemical Engineering Science. (2015) 138:685-688.Kowalczyk P, Sprynskyy M, Terzyk AP, Lebedynets M, Namieśnik J, Buszewski B. Porous structure of natural and modified clinoptilolites. J Colloid Interface Sci. (2006) properties of natural zeolite – Clinoptilolite – As a sorbent. Environment Protection Engineering (2012) 39(1):139.Moliner M, Willhammar T, Wan W, González J, Rey F, Jorda JL, Zou X, Corma A. Synthesis design and structure of a multipore zeolite with interconnected 12- and 10-MR channels. J Am Chem Soc. (2012) ;134(14):6473-8.
What is zeolite?
Zeolites are microporous crystalline aluminosilicates derived from the reaction of volcanic rocks, ash layers and alkaline groundwater. The Atlas of Zeolite Framework Types currently recognizes about 218 different Zeolite structures, of which 40 natural zeolites are known. Natural zeolites are listed by the USA Food and Drug Administration for human consumption (FDA GRAS Listings, 2006) and considered as non-toxic by the World Health Organization’s International Agency for Research on Cancer (IARC, 1997). Moreover, Codex Alimentarius Commission (1999) lists some zeolites as a granted substance in Organic Food Production and Plant Protection.
Most of us are familiar with the zeolites used in water softener systems. The zeolite core of the water softener absorbs large amounts of metals like calcium and magnesium from the water. Periodically, the zeolite in your water softener is flushed with highly concentrated salt water to flush out the metal ions and regenerate the zeolite for more absorption. The most common forms of zeolites used in water softeners are the natural aluminosilicates, gluconites (i.e. greensand), and synthetic permutite.
FDA GRAS List. Database of Select Committee on GRAS Substances (SCOGS) Reviews. Sodium Aluminosilicates. (http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=281).
European Food Safety Authority (EFSA) Panel on Food Contact Materials, Enzymes, Flavorings and Processing Aids (CEF). 2013a. EFSA Journal 11, 3155.
European Food Safety Authority The Panel of Additives and Products or Substances used in Animal Feed (FEEDAP). 2013b. EFSA Journal 11, 3039.
IARC., 1997a. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Supplement. Silica, Some Silicates, Coal Dust and para-Aramid Fibrils Vol 68 p. 506.
IARC., 1997b. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, “Zeolites other than Erionite” Vol 68 p.307-333.
SCOGS, 1979. Database of Select Committee on GRAS Substances (SCOGS) Reviews. Sodium Aluminosilicates. (http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=281).
lARC. 1987. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Supplement 7, Overall Evaluations of Carcinogenicity: An Updating of lARe Monographs. Volumes 1 to 42, Lyon, p. 203.
What is clinoptilolite?
Clinoptilolite is a naturally occurring hydrated alkali aluminosilicate that is one of the most abundant minerals in the zeolite family. Its structure consists of an outer framework of silica and alumina tetrahedra, within which clusters of water molecules and exchangeable cations (e.g., calcium, potassium, sodium) migrate freely, while larger metals preferentially gather inside.
See: https://youtu.be/RZhhrIC5QDkHealth A Tox Hazard Subst Environ Eng. (2012) 47(3):337-50.Sakthivel A, Iida A, Komura K, Sugi Y. The beta-zeolite synthesized by dry-gel conversion method without the use of sodium hydroxide: characterization and catalytic behaviors. J Nanosci Nanotechnol. (2009) 1:475-83.Li CH, Huang KL, Chi YN, Liu X, Han ZG, Shen L, Hu CW. Lanthanide-organic cation frameworks with zeolite gismondine topology and large cavities from intersected channels templated by polyoxo-metalate counterions. Inorg Chem. (2009) 48(5):2010-7.Zhang D, Zhang RQ. Silica nanoarchitectures with tailored pores based on the hybrid three- and four-membered rings. J Phys Chem B. (2006) 110(31):15269-74; Mintova S, Olson NH, Valtchev V, Bein T. Mechanism of zeolite A nanocrystal growth from colloids at room temperature. Science. (1999) 283(5404):958-60.(Ng TYS, Chew TL, Yeong YF, Jawad ZA, Ho CD. Zeolite RHO Synthesis Accelerated by Ultrasonic Irradiation Treatment Sci Rep (2019) 9:15062.Gordina NE, Prokof’ev VY, Kul’pina YN, Petuhova NV, Gazahova SI, Hmylova OE. Effect of ultrasound on the synthesis of low-modulus zeolites from a metakaolin. Ultrasonics Sonochemistry. (2016) 33: 210-219.Effects of ultrasound on the synthesis of zeolites: A review. Journal of Porous Materials. (2013) 20: 285–302.Jin H, Ansari MB, Park SE. Mesoporous MFI zeolites by microwave induced assembly between sulfonic acid functionalized MFI zeolite nanoparticles and alkyltrimethylammonium cationic surfactants. Chem Commun (2011) 14;47(26):7482-4.Panzarella B, Tompsett GA, Yngvesson KS, Conner WC, Microwave Synthesis of Zeolites. 2. Effect of Vessel Size, Precursor Volume, and Irradiation Method. J. Phys. Chem. B (2007), 111, 44, 12657-12667Conner WC, Tompsett G, Lee KH, Yngvesson KS. Microwave Synthesis of Zeolites: 1. Reactor Engineering. J. Phys. Chem. B (2004), 108, 37: 13913-13920.
What is Advanced TRS?
Advanced TRS contains nano-clinoptilolite, which is a smaller version of micronized clinoptilolite, with stable chemical and physical characteristics. Its main advantage comes from its tremendously higher pore accessibility and ability to penetrate more effectively to wherever toxins are found. Clinical studies reported to date do not dispute that nano-clinoptilolite is a safe and effective product. Clinoptilolite itself has been shown to:
● Bind heavy metals and over 80,000 toxins
● Adjust the balance of vital nutrients like iron & calcium
● Support intestinal microflora and pH
● Promote healthy immune function
Advanced TRS is a REFINED formula utilizing nano-sized particles to enhance the body’s natural detoxification efforts at the cellular level.
https://www.youtube.com/watch?v=IwIe4A4zx6E
What is a nano-sized particle?
The classic definition is that a particle is considered to be nano-size when it is less than 100 nanometers in size. This definition is a non-limiting functional definition that arose when scientists discovered unique properties in certain materials with nanometer-sized dimensions.
https://youtu.be/B-nrrstoO_E
What is the size of the zeolite particles in Advanced TRS?
The particle sizes in Advanced TRS are between 10 and 250 nanometers, with the most common size somewhere in-between those two values.. The active site, or pore size is approximately 0.9 nanometers.
https://youtu.be/sA4saOn_ykk
How does Advanced TRS help the body to remove heavy metals and toxin?
The strong attraction of zeolites for toxins is the result of the way the elements oxygen, silicon, aluminum, and alkali metals (e.g. lithium, sodium, potassium) are arranged inside the material. The Silicon-Oxygen and Aluminum-Oxygen bonds that create the nanometers-sized hollow cages inside the zeolite are bulky and rigid. The strong bonds between these elements leave the interior space within the cage with a negative electrical charge, and elements and molecular fragments with positive charge are strongly adhered, sometimes by multiple connections, making it very difficult for the captured species to escape. Zeolites, like that in Advanced TRS, have the capability of absorbing any metal found in a positively charged state. The actual amounts will depend on which element, if it is a combination of elements, and the form of these elements (i.e. if they are dissolved or part of larger metallo-organic complexes.).
Noble metals like gold and platinum are usually neutral and would have little affinity to advanced TRS.
https://youtu.be/w6G3QM0vz8APositive charge means that an object is not electrically neutral but has fewer balancing negative charges than positive charges.
The concept of charge comes from everyday observation of static cling in the laundry. The reason why you get static cling, is that the two objects, you and your laundry item, oppositely match each other electrically so that when they come together they are electrically neutralized and stick. At the microscopic level, it means one has more electrons than it needs and the other does not have enough. When the two things come together the extra electrons from one can be donated to the other object. Sometimes the electrons can’t really leave their parent object so the two objects “cling” together. When you get an electrical shock on touching something, it means the extra electrons from one object have jumped across the air, into the other object, bringing the two items together. That creates a “spark” and you might feel a pain or pinch at the point closest to contact.
How is Advanced TRS different from other forms of liquid zeolite available on the market?
Advanced TRS is different in many ways: Through Coseva’s proprietary processes, the zeolite particle is nano-sized and stabilized in water which allows it to be easily assimilated. Additionally, Advanced TRS is the purest form of clinoptilolite available because it is Lab Grown in a clean laboratory facility, using state of the art technology and science.The Lab Grown zeolite in Advanced TRS is an improvement on nature since its synthesis occurs from only well-characterized precursors, in a clean, sterile environment.
https://youtu.be/bm5YtKqbeNs
How long does Advanced TRS stay in the body?
It depends on the individual, as each person’s digestive system works a little differently. In the 1980’s, Mayo Clinic researchers measured digestion time in 21 healthy people. Total transit time, from eating to elimination in stool, averaged 53 hours. The average transit time through just the large intestine (colon) was 40 hours, with significant difference between men and women: 33 hours for men, 47 hours for women.
Taking Advanced TRS every day will result in a steady state level of zeolite in your digestive tract. Once you stop taking Advanced TRS it takes a couple days for Advanced TRS to fully clear out.
Metcalf AM, et al. Simplified assessment of segmental colonic transit. Gastroenterology. 1987; 92:40.https://youtu.be/VUr842PKWmg
Where does Advanced TRS go in the body?
Because the zeolite molecule in Advanced TRS is surrounded by layers of water, it can travel in the body wherever water goes.
What ingredients are in Advanced TRS?
Laboratory-made clinoptilolite zeolite and ultra-purified water.
Is the purified water in Advanced TRS processed with activated charcoal or coconut husks?
No, it’s filtered with standard polypropylene pharmaceutical grade filters then through a reverse osmosis filter to produce 18 megohm water.
Will Advanced TRS affect a pacemaker, artificial joint, dental work, mercury fillings, or any surgical implant?
Advanced TRS will not leach metals from a fully processed medical implant or device. They will not be attracted to or removed by the zeolite.
Will Advanced TRS interfere with the effectiveness of a Copper non-hormonal IUD?
No. Copper IUDs work as a physical barrier to conception, and Advanced TRS has no impact on this function.
Will Advanced TRS remove the zinc, iodine and silver supplements I take?
Iodine is negatively charged and will not bind to Advanced TRS clinoptilolite – which is negatively charged. Zinc and silver – being positively charged – may have some affinity for the zeolite.
Coseva recommends that micronutrient minerals be taken at least 4 hours before or after the Advanced TRS. Once in the body, minerals which are essential for health, are very quickly bonded to other substances which neutralize any ionic charge and therefore preserve them for use by the body. Pollutants, like heavy metals which are not useful for health, are not protected by the body and can therefore be picked up by the zeolite. The 4 hour dose interval is to allow the body to protect what it needs.
Iodine, which is not a metal, will be used by the body and the zinc will also be protected by the body. The silver (elemental), as a noble metal, has no charge to attract the zeolite.
Will Advanced TRS be adversely affected by an x-ray?
As x-rays are an ionizing radiation and not a particle/molecule, the x-ray will not have a negative effect on the zeolite in Advanced TRS.
Are there clinical studies that confirm capture of metals from tissues?
Yes. Clinoptilolite’s ability to capture toxins is well documented on pubmed.gov and medline.gov. Some of these studies are referenced in our white paper, but there are so many that it is by no means a comprehensive list.
Is Advanced TRS FDA approved?
Advanced TRS has not been evaluated by the FDA. Clinoptilolite zeolite has been recognized as safe by the FDA, having been granted GRAS status.
Is Advanced TRS safe?
Manufactured clinoptilolite zeolite has been recognized by the FDA as safe, having been granted GRAS status.
Is Advanced TRS safe for children?
We have seen no evidence that Advanced TRS is not safe for children. Always consult with your physician before taking any supplements including Advanced TRS. As a rule of thumb, the usage rate is based on a person who weighs 150 pounds. Therefore, 150 pounds divided by 5 sprays is equal to 30 pounds per spray.
Is Advanced TRS safe to take during breast feeding and/or pregnancy?
We have seen no evidence that Advanced TRS is not safe for women who want to become pregnant, are pregnant, or have recently been pregnant. Advanced TRS is not fat soluble. Always consult with your physician before taking any supplements including Advanced TRS.
Can Advanced TRS be taken the day of vaccination?
There is no evidence that Advanced TRS will interfere with the effectiveness of the vaccination.
Where does Advanced TRS go in the body?
Because the zeolite molecule in Advanced TRS is encased in a water cluster, it can travel in the body wherever water goes.
Can you use Advanced TRS to detox animals?
Yes, and studies have shown manufactured clinoptilolite to be a safe method for detoxing animals.
At what temperature should I store Advanced TRS?
Ideally, Advanced TRS should be kept at room temperature of 50-80 F. Freezing or thawing will not alter the solution. Warm temperatures below the boiling point will not alter the solution.
Does Advanced TRS have an expiration?
The zeolite in Advanced TRS can remain stable for up to 5 years as long as storage and handling instructions are followed.
What heavy metals and toxins can Advanced TRS remove from the body?
Advanced TRS is engineered to bind to any element or small molecule that has a positive ionic charge, such as mercury, lead, nickel, aluminum, cadmium, arsenic, ammonia etc.
How do I know if Advanced TRS will remove certain toxins?
Advanced TRS removes elements with a positive ionic charge. If a toxin has a positive ionic charge, it can be removed. If it does not have a positive ionic charge, it will not be removed.
Will Advanced TRS remove radiation and/or radioactive elements?
Advanced TRS will only remove a physical particle that is positively charged. It will not remove radiation such as x-rays because the x-ray exists only transiently in your tissues during the procedure. However, ATRS may remove some of the acidic byproducts created by such energies.
Does Advanced TRS target certain heavy metal toxins over others?
Clinoptilolite has different binding strength for different positively charged toxin, with stronger affinity for larger, electron-rich metals like mercury and lead, for example.
Does Advanced TRS remove essential nutrients from the body?
Essential minerals are converted to a neutral salt form for use by our bodies. The zeolite is not attracted to the lesser ionic charges that these nutrients possess. Toxins, however, are not used in the body and thus are not converted to salts, and Advanced TRS can bind to them.
Does Advanced TRS chelate metals found inside the cell? Or is it just metals found in the blood?
Your body seeks balance. Advanced TRS will rebalance toxins located both the blood, lymph system and tissues, but first removing accessible ionized forms. Once they are removed, trapped materials will be naturally released from the cells in your body, and be further removed.
Will Advanced TRS remove fluoride?
Fluoride is negatively charged and therefore will not be removed from the body by Advanced TRS.